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Intrahepatic cholangiocarcinoma (ICC) is a rare hepatic malignancy with a poor prognosis. It is known that Hepatitis B is both a risk factor and a prognosis factor for ICC. However, little is known about the clinical, pathological and radiological characteristics of ICC patients with hepatitis B virus (HBV) infection.
A systematic review of relevant literature was performed using PubMed and EMBASE databases. HBV-associated ICC revealed several unique and interesting features, it was found to have higher alpha-fetoprotein (AFP), cancer antigen 19-9 (CA 19-9) levels, capsule form....[more]
miRNA 200 Family Expression is a Strong Predictor for Recurrence Following Liver Resection for Breast Cancer Liver Metastases
Nicolae Bacalbaşa, Irina Bălescu, Veronica Ilie, Raluca Florea, Andrei Sorop, Vladislav Braşoveanu, Mihaela Vilcu, Iulian Brezean, Simona Dima, Irinel Popescu
Article DOI: 10.21614/sgo-24-1-15
Read article Although only a small percent of breast cancer patients are diagnosed in metastatic stages, a significantly higher percent will develop disseminated recurrences at a certain point of their evolution, this event being responsible for a high number of cancer relate deaths.
In recent years a particular attention was paid for identifying the factors which might be responsible for the development of metastatic disease.
The current study included 27 patients submitted to surgery for breast cancer liver metastases in Dan Setlacec Center of Gastrointestinal Diseases and Liver Tra....[more]
Preoperative Ascites and/or Pleural Effusion Was a Predictor of Massive Albumin Use After Liver Transplantation
Naoko Kamo, Toshimi Kaido, Ryuji Uozumi, Shintaro Yagi, Hideaki Okajima, Shinji Uemoto
Article DOI: 10.21614/sgo-24-1-22
Read article Background: Albumin (Alb) is often administered for patients undergoing liver transplantation (LT). However, the current status of Alb use after LT is unclear. We examined the current status of postoperative Alb administration and factors associated with massive Alb use after LT.

Methods: A total of 122 consecutive patients who underwent adult-to-adult LT between January 2013 and August 2017 were divided into 2 groups according to total amount of Alb used after LT: High group, Alb 1000 g; and Low group, Alb <1000 g.
Characteristics of postoperative Alb u....[more]
Neuroendocrine Tumuors of the Pancreas - Surgical Treatment and Prognostic Factors
Tsonka Lukanova, Cvetan Trichkov, Vasil Mihaylov, Ivelin Takorov, Maria Yakova, Radoslav Kostadinov, Nikola Vladov
Article DOI: 10.21614/sgo-24-1-31
Read article Background: Surgery is still the only curative treatment for patients with pancreatic neuroendocrine tumours (pNETs). Prognosis depends mainly on tumour characteristics.

Methods: The single-centred retrospective cohort study consisted of 58 patients with a histological confirmation of pNET, who were operated over a time span of 10 years. The analysis is focused on the type of surgery, post-operative morbidity, survival rates and prognostic factors.

Results: Median age at diagnosis was 53.28 years (SD 9.85; 21-81). The operative interventions p....[more]
Alpha-Fetoprotein, Alpha-Fetoprotein-L3, Protein Induced by Vitamin K Absence, Glypican 3 and Its Combinations for Diagnosis of Hepa....
Răzvan Cerban, Carmen Ester, Speranţa Iacob, Mihaela Ghioca, Liliana Paslaru, Radu Dumitru, Mugur Grasu, Georgiana Constantin, Irinel Popescu and Liliana Gheorghe
Article DOI: 10.21614/sgo-24-1-37
Read article Introduction: Despite its limitations, alpha-fetoprotein (AFP) is still the most common used serum marker for hepatocellular carcinoma (HCC). Alpha-fetoprotein-L3 (AFP-L3), protein induced by vitamin K absence (PIVKA-II) and Glypican-3 (GPC-3) have been proposed as complementary biomarkers but their role is still controversial.

Aims and Methods: We prospectively included 101 patients with HCC and 52 control patients with liver cirrhosis with the aim to investigate the diagnostic performance of AFP, AFP-L3 PIVKA-II, and GPC-3 as single markers or in combination....[more]
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Print ISSN: 2559 - 723X

ISSN-L: 2559 - 723X

ISSN online: 2601 - 1700

Surgery, Gastroenterology and Oncology is indexed in Scopus, CrossRef (DOI: 10.21614/sgo)

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