Surgery, Gastroenterology and Oncology

Read article Background: In the view of need for early identification of cases of Acute Pancreatitis [AP] who may end up dying in spite of rigorous treatment measures, many scores have been proposed claiming to be superior in doing so. This study compares 5 newer scores which are possible to be assessed in first few hours of admission with mortality as outcome.

Methods: It's a retrospective study of 200 consecutive cases of first episodes of AP in a tertiary care centre in India. Scores were compared at their optimal cut off values by sensitivity, specificity, Positive and N....[more]

Read article Introduction: Laparoscopic cholecystectomy (LC) has replaced open technique as the main surgical intervention in the treatment of gall bladder stones. There are different clinical and radiological predictors that are indicators for technically difficult LC.

Aim of the work: The aim of this study was to identify the clinical and radiological variables associated with difficult LC.

Methods: During the period from March 2018 to March 2021, 452 adult patients who presented with symptomatic gall bladder stones underwent LC. Different clinical and rad....[more]

Read article Background: Circulating cryoglobulins are detected in 40-60% of patients with HCV chronic infection, and cryoglobulinemic vasculitis is observed in 15% of cases.

Methods: We included 24 patients with HCV-related mixed cryoglobulinemia (MC) and 8 patients with asymptomatic HCV cryoglobulinemia, between 2016-2019. All patients received DAA therapy: 22 patients with ombitasvir paritaprevir ritonavir and dasabuvirand 10 patients with ledipasvir sofosbuvir. The primary endpoint was complete clinical remission of vasculitis at week 24.

Results: All 5 pa....[more]

Read article Objective: This study was designed to determine the relationship between metabolic syndrome as a risk factor for colorectal cancer.

Background: Overweight and obesity are leading risks for global deaths. Although the increase in obesity over the last 35 years has been most dramatic in the US and western industrialized countries, similar trends have also been seen in urban areas of many developing countries. There are multiple common health consequences of an elevated body mass index, including risk for several metabolic disorders, some cancers and ultimately i....[more]