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Since its inception, IASGO and its founders have played a major role in promoting and improving liver transplantation (LT). Thomas Starzl was an Honorary President of IASGO. Henri Bismuth is an Honorary President, Masatoshi Makuuchi is the current President and Sung-Gyu Lee is an Honorary Vice-President of IASGO.

In this special issue, the two editors present a collection of experiences from across the world, leveraging the global reach of the IASGO, a unique organization, open to specialists from all countries.

Kantoku Nagakawa et al. from Nagasaki Univer....[more]
Inflammatory Responses in Liver Transplantation
Kantoku Nagakawa, Akihiko Soyama, Susumu Eguchi
REVIEW, Mar 2021
Article DOI: 10.21614/sgo-26-326
Read article Successful liver transplantation requires proper mitigation of stress responses. Systemic effects caused by liver cirrhosis, invasive surgery, ischemia-reperfusion injury, rejection, and infection, all of which are relevant to liver transplantation, are mediated by inflammatory factors.
Recently, the detailed mechanisms of inflammation have been elucidated. Damageassociated molecular patterns (DAMPs) released from cells damaged by ischemia or injury, or pathogen-associated molecular patterns (PAMPs) released by pathogens, are recognized by internal cell receptors or cell surfac....[more]
Domino Liver Transplantation: Current Status
Inês Barros, Élia Mateus, João Santos Coelho, Américo Martins, Eduardo Barroso, Fernando Nolasco, Hugo Pinto-Marques
REVIEW, Mar 2021
Article DOI: 10.21614/sgo-26-319
Read article Domino Liver transplant (DLT) is a strategy to address organ shortage and expand the liver donor pool for liver transplantation. Despite offering some unique technical challenges, DLT appears to be a safe and reasonable option to be considered for selected patients who would otherwise not benefit from liver transplantation.
However, the benefit of expanding the donor pool must be balanced against the risk of disease transmission.In this review, we present where the DLT currently stands worldwide and our own experience with this procedure.
Liver Transplantation and Surgery in the Management of Hepatocellular Carcinoma
Massimo Malagó, Dimitri Aristotle Raptis, Charles J. Imber, Giovanni Dalla Serra, Oskar Kornasiewicz
REVIEW, Mar 2021
Article DOI: 10.21614/sgo-26-320
Read article Hepatocellular carcinoma (HCC) is the second cause of cancer–related deaths worldwide constitutes a major global health problem. Although our understanding of the molecular pathogenesis of hepatocellular HCC has improved, detected driver mutations are not yet sufficiently reliable therapeutic targets.
The modern management of HCC is conceived only within multidisciplinary schemes. Current systemic therapies are not curative and surgical treatments remain the only potential curative treatments for selected patients with early stage HCC.
The role of parenchyma sparing ....[more]
Liver Transplantation During COVID-19 Pandemic: Experience of a Single High-Volume Italian Center in the Eye of the Storm
Luciano De Carlis, Andrea Lauterio, Riccardo De Carlis
ORIGINAL PAPER, Mar 2021
Article DOI: 10.21614/sgo-26-321
Read article The first wave of coronavirus disease 2019 (COVID-19) pandemic accounted for roughly 35,000 deaths in Italy and was mainly concentrated in the industrial north of the country.
Despite Italy returned to a partial lockdown during December, the number of people dying in the second wave has now surpassed the toll recorded in the first. This report aims to provide a snapshot of the impact of COVID-19 on liver transplantation activity in our Institution, with special regard to the measures put in place to guarantee through the two waves of the pandemic.
LT activity continued in....[more]
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Print ISSN: 2559 - 723X

ISSN-L: 2559 - 723X

ISSN online: 2601 - 1700

Surgery, Gastroenterology and Oncology is indexed in Scopus, CrossRef (DOI: 10.21614/sgo)



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