Surgery, Gastroenterology and Oncology

Purpose: Failure and recurrence are concerns in nonoperative management (NOM) for acute appendicitis (AA) and interval appendectomy (IA). The goal of the study was to identify predictors of failure and recurrence in patients with AA who underwent NOM.

Methods: A total of 348 adults with appendicitis were treated in our department from April 2016 to October 2021. Among these patients, 337 who did not undergo emergency surgery were divided into those for whom NOM was unsuccessful, leading to unplanned surgery (n=28) and tho....[more]

Background: Hepatocellular carcinoma (HCC) is a major type of liver tumor. It represents up to 90% of all liver malignancies. There are currently no reliable tumor markers or imaging technologies that can accurately diagnose early HCC. The use of circulating micro-RNAs (miRNAs or miR) as a potential tool for early detection of HCC has become an emerging area of study. Objectives: This study aimed to evaluate the role of miR-23b and miR-331 as biomarkers in HCC and chronic hepatitis C (CHC) patients.

Patients and Methods: Thi....[more]

Background and Aim: to compare the early outcome results of laparoscopic versus open management as laparoscopic management seems to have multiple attractions for surgeons with marked controversy.

Materials and Methods: All patients of Gastroduodenal perforation were included and randomized for laparoscopic or open repair. The data obtained from the diagnostic flowchart, operative details, postoperative morbidities, and mortalities were collected for statistical analysis.

Results: sixty-six patients were assigned to....[more]

Introduction: Spontaneous hemorrhage resulting from rupture of an adrenal artery is extremely rare. The exact pathophysiology of this phenomenon remains unclear in patients not assuming oral anticoagulant or antiplatelet therapies.

Case report: A 55-year-old male with no comorbidities was referred to our emergency department with worsening abdominal pain after iterate episodes of violent coughing. The abdominal CT scan revealed a large retroperitoneal hematoma resulting from the rupture of the superior adrenal....[more]