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We review herein the available data regarding the potential relationship between antidepressants and breast cancer. According to some studies, the biological rationale leading correlation among antidepressants and mammary carcinogenesis is represented by the increase in prolactin levels and by the promotion of cell proliferation.
However, these studies seem to be spoiled by an unsatisfactory statistical design and by the lack of a good control for confounding elements. Thus, experimental and clinical data remain controversial, even though recent studies tend to exclude a causat....[more]
Clinical and Biological Characteristics of Breast Cancer in Women with Mammary Paget's Disease: A Retrospective Study of 36 cases
Mahmoud Al-Balas, Margherita Serra, Hamzeh Al-Balas, Donatella Santini, Mario Taffurelli
ORIGINAL PAPER, Dec 2020
Article DOI: 10.21614/sgo-25-5-236
Read article Objective: Identification of clinical and biological characteristics of breast cancer in women with mammary Paget's disease (MPD).

Methods: We performed a retrospective analysis for 36 women with a primary diagnosis of mammary Paget's disease, patients were treated in Sant Orsola-Malpighi Breast Unit in Italy, between 2000 and 2016. Patients demographics, clinical data, radiologic and pathologic reports were extracted from electronic health records.

Result: 36 cases of patients with a diagnosis of MPD were involved. The mean age was 64.28 years....[more]
Does Donor Liver Extraction Time Affect Early Allograft Function in Deceased Adult Liver Transplant Recipients?
Mohamed Ghazaly, Veena Surendrakumar, Navneet Tiwari, Pulkit Sethi
ORIGINAL PAPER, Dec 2020
Article DOI: 10.21614/sgo-25-5-241
Read article Background: Recent work has identified time taken to remove a donor liver during organ retrieval (the extraction time) as a previously unrecognized variable affecting transplant outcome. We evaluated the effect of extraction time on early graft function in our own practice in a busy liver centre. Patients and

Methods: 218 recipients of liver grafts transplanted at our centre (Addenbrooke's, Cambridge) between October 2014 and October 2017 were evaluated. Early graft function was assessed by model for early allograft function (MEAF) score in both univariate and m....[more]
Results of an Enhanced Recovery after Surgery Protocol for Upper Gastrointestinal Surgery at a Super-Tertiary Referral Hospital in T....
Thammawat Parakonthun, Thikhamporn Tawantanakorn, Jirawat Swangsri, Tharathorn Suwatthanarak, Nicha Srisuworanan, Voraboot Taweerutchana, Chainarong Phalanusitthepa, Atthaphorn Trakarnsanga, Thawatchai Akaraviputh, Asada Methasate, Vitoon Chinswangwatanakul
ORIGINAL PAPER, Dec 2020
Article DOI: 10.21614/sgo-25-5-248
Read article Background: Enhanced recovery after surgery (ERAS) protocol has been shown to reduce recovery period and postoperative complications. This prospective study aimed to evaluate the short-term outcomes of ERAS in patients who underwent upper gastrointestinal (UGI) surgery.

Methods: Patients who underwent surgery for benign or malignant diseases of the esophagus, esophagogastric junction, or stomach during October 2018-December 2019 were included. Outcomes compared between ERAS and conventional care (CC) included length of hospital stay (LOS), postoperative complica....[more]
Gastric and Extragastric GIST Presentation and Management, in a Tertiary Referral Center - A Ten Years Retrospective Cohort Study
Ahmed Abdallah, Mosab Shetiwy, Islam A Elzahaby, Basel Refky, Khaled AbdElwahab, Osama Eldamshety, Mahmoud Abdelaziz, Amr Abouzid, Nirmeen Megahed, Islam H Metwally
ORIGINAL PAPER, Dec 2020
Article DOI: 10.21614/sgo-25-5-269
Read article Introduction: Gastrointestinal stromal tumor (GIST) is the commonest mesenchymal tumour of the gut. However, the epidemiology of the disease in Egypt is not adequately studied.

Methods: A retrospective cohort study was conducted on patients treated for GIST from June 2008 to April 2018 in a tertiary center. Sixty-two cases were eligible for the study.

Results: The stomach was the commonest tumor site. The incidence of tumor residue was higher in extra-gastric (intestinal) GISTs. Laparoscopy was more frequently used in gastric GIST surgery. Overall....[more]
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Print ISSN: 2559 - 723X

ISSN-L: 2559 - 723X

ISSN online: 2601 - 1700

Surgery, Gastroenterology and Oncology is indexed in Scopus, CrossRef (DOI: 10.21614/sgo)



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