Surgery, Gastroenterology and Oncology

Read article Background: Surgical resection with en-bloc lymphadenectomy is the hallmark of curative therapy for gastric cancer patients. The favoured surgical technique worldwide has been open gastrectomy for a long time. This procedure however, is connected to significant morbidity. Compared to open procedures, multiple meta-analyses have demonstrated a benefit in the short-term results of laparoscopic gastrectomy.


Objective: Comparison of the short-term advantages of radical gastrectomy with dissection D2 (laparoscopic and open in gastric cancer patients).....[more]

Read article Objective: Papillary thyroid carcinoma (PTC) has a high rate of lateral neck node metastases, lymph node metastasis (LNM) is a vital prognosis factor. The aim of this study was to evaluate morbidity and outcomes of therapeutic lateral neck dissection papillary thyroid cancer (PTC) with lateral lymph node metastasis (LLNM).

Methods: We conducted a retrospective analysis of 78 PTC patients who underwent neck dissections for the management of lateral cervical metastases from January 2010 and January 2020.

Results: 35.9% and 16.7% presented multif....[more]

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Cutaneous squamous cell carcinoma is the second most common skin cancer. Cemiplimab, an antiPD-1 monoclonal antibody, is the first immunotherapy approved for patients with locally advanced cSCC. Phase I and II studies showing high antitumor activity and good tolerability of cemiplimab. However, very little data is available on cemiplimab in real life and in frail, elderly and immunocompromised patients. We report the case of an elderly patient (84 years old) affected by metastatic cSCC. The patient performed 16 cycles of treatment with cemiplimab with complete pathological respons....[more]

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Neuroendocrine tumors of the pancreas (NETP) are rare malignancies that originate from pancreatic neuroendocrine cells and may be functional in nature through the clinical picture secondary to hormonal hypersecretion. These tumors can be detected incidentally by imaging in patients presenting with specific syndromes or as a result of the mass, volumetric effect of metastases and primary tumors. This article presents two cases diagnosed with NETP, of two men aged 58 and 77 years respectively in the Hospital, detected by CT and subsequently confirmed histopathologically, who present....[more]

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Toxoplasma gondii is a parasitic infection widespread worldwide, being the prerogative of AIDS patients. We present a case of reactivated T. gondii in a 30-year-old, HIV-positive patient who presented with secondary partial and generalized seizures, hepatitis C virus infection, hematological abnormalities. MRI examination identifies a 14/12 mm left paramedian cortico-subcortical lesion with intense peripheral contrast uptake and associated edema. The importance of cerebral radiographic examination in HIV patients is discussed in this paper.

INTRODUCTION

Toxoplasm....[more]