Surgery, Gastroenterology and Oncology

Read article The hepatic artery (HA) related complications after living donor liver transplantation (LDLT) remains an important cause of increased risk of post-transplant mortality. The timing of occurrence of hepatic artery thrombosis (HAT) after transplantation and the timely intervention are the determining factors in the survival of the recipients. Re-exploration and revision of the hepatic artery anastomosis or medical treatment with urokinase therapy are the lifesaving treatment options. We describe our successful outcome after arterial urokinase infusion as an initial therapy for the LDLT ....[more]

Read article Background: Rectal neuroendocrine tumor (NET)s that are <10mm in diameter can be treated with local excision including endoscopic resection. Endoscopic mucosal resection (EMR) of rectal NETis often associated with involvement of the resection margin. Endoscopic submucosal dissection (ESD) has more histologically complete resection. However, ESD can lead to more serious complications and longer procedure time than EMR.
Endoscopic mucosal resection using band ligation (EBL) is a new technique for eliminating the rectal NET. The aim of the this study is to evaluate the ther....[more]

Read article Introduction: Pancreatic intraductal papillary mucinous neoplasms (IPMN) are recognized as pre-malignant lesions, corresponding to less than 3% of all pancreatic exocrine neoplasms. The study objectives were: to evaluate the surgical results of our institution, to identify factors predicting malignancy in IPMN and to assess the validity of recently introduced IPMN guidelines in our population.

Methods: A single center, retrospective study in patients submitted to surgical resection for IPMN was conducted, between 1 2008-6 2016, to identify predictive factors f....[more]

Read article Background: The value of preoperative biliary drainage (PBD) on the surgical outcome after pancreaticoduodenectomy (PD) is still a point of controversy.The aim of this study was to identify the impact of biliary drainage (BD) prior to PD on the postoperative outcome.
Methods: The data of patients, who underwent PD from February 2009 to February 2017, were retrospectively studied. A comparison was performed between 2 groups of patients; group A (with PBD) and group B (without PBD), according to preoperative, operative and postoperative data.
Results: PD....[more]

Read article Background: In Egypt, newly diagnosed cases of cholangiocarcinoma are increasing annually. Several reports from Nile Delta show high levels of heavy metals and organocholorine pesticides in the soil and water. We assess serum levels of Heavy metals [Zinc (Zn), lead (Pb), Cobalt (Co), Cadmium (Cd), Chromium (Cr) and Iron (Fe)] as markers of exposure in cholagiocarcinoma patients and healthy controls from the Nile Delta in Egypt and its correlation with tumor differentiation and tumor marker CA 19-9.

Methods: We included 45 cholangiocarcinoma patients and 20 hea....[more]

Read article Background Aims: The aim of this study was to investigate the efficacy and safety of the oral fluoropyrimidine derivativeS-1 in elderly patients with unresectable pancreatic cancer.

Methods: Patients were eligible if they were at least 70 years old and had unresectable pancreatic carcinoma. S-1 was administered orally twice daily after meals at doses of 80, 100, and 120 mg day forbody surface areasfor 28 consecutive days, followed by a 14-day rest period. Administration was repeated until the appearance of disease progression or unacceptable toxicity.

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Read article Background Aims: We conducted a trial to evaluate the FSSG questionnaire and GerdQ questionnaire for diagnostic accuracy given correlation with clinical findings.

Methods: One hundred three consecutive patients who were seen in the Yokohama City University hospital with a gastrointestinal symptom in May 2011 were enrolled as potential subjects. Of these, 94 patients underwent upper gastrointestinal endoscopy, and clinical symptoms were evaluated using both the FSSG and GerdQ questionnaires.

Results: There were 94 subjects with GERD and 9 subje....[more]

Read article Introduction: Acute large bowel obstruction is a rare presentation of pancreatic cancer, with only six cases described in the revised literature. In all those cases, diagnosis was made either intraoperatively or post-mortem.

Case presentation: A 63-year-old man presented in the emergency room with 4 days of bowel constipation associated with abominal pain and distention. Abdominal CT revealed a narrowing at the colonic splenic flexure and the colonoscopy revealed extrinsic compression at 40 cm from the anal verge. The patient was submitted to emergent explorato....[more]