Surgery, Gastroenterology and Oncology

Read article Professor Masaki Kitajima graduated from the Keio University School of Medicine in 1966. After receiving his Ph.D. degree in 1975, he spent two years as a fellow at Harvard Medical School and Massachusetts General Hospital, Boston, USA.
In 1989, he returned to Japan and was appointed a professor at the Keio University School of Medicine. He founded the Department of Surgery at Keio University and became its Chairman (see Full Biography in Online Appendix).

Over the years, twenty surgeons from his department have been appointed as professors. He became Professor Emer....[more]

Read article Background: Corrosive substances are common household substances that can be ingested either accidentally or with suicidal intent. Contents of the corrosives range from acid to alkali in varied concentrations. Corrosive ingestion represents serious problems with varied presentation and long term complications. Present study aims to explore the clinical-endoscopic profile and outcome of corrosive ingestion.

Methods: We analysed clinical, endoscopy characteristics, outcome and complications of all consecutive patients presented with corrosive ingestion from August....[more]

Read article Background: Nonalcoholic fatty liver disease (NAFLD) is more common in subjects with obesity and diabetes mellitus (DM). Hypothyroidism is a risk factor for development of NAFLD. The study was done to assess the association of hypothyroidism with NAFLD and severity of NAFLD.

Methods: The study was carried out on 50 NAFLD patients. Among them 25 patients had no hypothyroidism and 25 patients had hypothyroidism. Histological diagnosis of NAFLD (non-NASH & NASH), based on NAFLD activity score (NAS) was done. Stages of fibrosis was evaluated by separate fibrosis sco....[more]

Read article Safe hepatectomy for the paracaval portion of the caudate lobe is technically demanding. We propose central hepatectomy using the hilar approach for resection of the paracaval portion.The right liver with the caudate lobe was totally mobilized from the inferior vena cava. Central hepatectomy with or without middle hepatic vein (MHV) resection was performed by dividing the right anterior and left medial sections vertically toward the inferior vena cava.
The bilateral Glissonian pedicles were widely exposed (hilar approach), and the liver parenchyma including the paracaval portion ....[more]

Read article A 66-year-old man was found to have a 4 cm mass in the distal transverse colon that was biopsied on a diagnostic colonoscopy performed for occult anemia. Pathology showed incomplete removal of a tubulovillous adenoma with high-grade dysplasia. The patient underwent surgical resection, with final pathology demonstrating two 5 mm foci of large cell neuroendocrine carcinoma (LCNEC) within a background of tubulovillous adenoma, and 1 of 8 positive lymph nodes.
Poorly-differentiated neuroendocrine tumors (NET) are termed neuroendocrine carcinoma (NEC), and are extremely rare. Colore....[more]

Read article Primary gastric squamous cell carcinoma is a very rare cancer whose mechanism has not been clearly elucidated. To date, less than 100 cases have been reported. However, only one case was reported to be presented as a subepithelial tumor. A 69-year-old woman complained of melena, dizziness for one month, and anorexia for two months. Esophagogastroduodenoscopy revealed a large bleeding subepithelial tumor in the upper body of the stomach.
Endoscopic biopsy diagnosed with gastric squamous cell carcinoma. In abdominal computed tomography (CT), large, poorly heterogeneous enhancing, i....[more]