Surgery, Gastroenterology and Oncology
Vol. 25, No. 5, Dec 2020
Implications of Antidepressants Use in Breast Cancer: A Brief Review
Angela Strazzanti, Federica Martorana, Eva Intagliata, Katia Lanzafame, Giuliana Pavone, Sergi Mauro, Gangi Santi, Livia Manzella, Francesco Basile, Claudio Trovato
REVIEW, Dec 2020
Article DOI: 10.21614/sgo-25-5-229
Read article We review herein the available data regarding the potential relationship between antidepressants and breast cancer. According to some studies, the biological rationale leading correlation among antidepressants and mammary carcinogenesis is represented by the increase in prolactin levels and by the promotion of cell proliferation.
However, these studies seem to be spoiled by an unsatisfactory statistical design and by the lack of a good control for confounding elements. Thus, experimental and clinical data remain controversial, even though recent studies tend to exclude a causat....[more]
Clinical and Biological Characteristics of Breast Cancer in Women with Mammary Paget's Disease: A Retrospective Study of 36 cases
Mahmoud Al-Balas, Margherita Serra, Hamzeh Al-Balas, Donatella Santini, Mario Taffurelli
Article DOI: 10.21614/sgo-25-5-236
Read article Objective: Identification of clinical and biological characteristics of breast cancer in women with mammary Paget's disease (MPD).

Methods: We performed a retrospective analysis for 36 women with a primary diagnosis of mammary Paget's disease, patients were treated in Sant Orsola-Malpighi Breast Unit in Italy, between 2000 and 2016. Patients demographics, clinical data, radiologic and pathologic reports were extracted from electronic health records.

Result: 36 cases of patients with a diagnosis of MPD were involved. The mean age was 64.28 years....[more]
Does Donor Liver Extraction Time Affect Early Allograft Function in Deceased Adult Liver Transplant Recipients?
Mohamed Ghazaly, Veena Surendrakumar, Navneet Tiwari, Pulkit Sethi
Article DOI: 10.21614/sgo-25-5-241
Read article Background: Recent work has identified time taken to remove a donor liver during organ retrieval (the extraction time) as a previously unrecognized variable affecting transplant outcome. We evaluated the effect of extraction time on early graft function in our own practice in a busy liver centre. Patients and

Methods: 218 recipients of liver grafts transplanted at our centre (Addenbrooke's, Cambridge) between October 2014 and October 2017 were evaluated. Early graft function was assessed by model for early allograft function (MEAF) score in both univariate and m....[more]
Results of an Enhanced Recovery after Surgery Protocol for Upper Gastrointestinal Surgery at a Super-Tertiary Referral Hospital in T....
Thammawat Parakonthun, Thikhamporn Tawantanakorn, Jirawat Swangsri, Tharathorn Suwatthanarak, Nicha Srisuworanan, Voraboot Taweerutchana, Chainarong Phalanusitthepa, Atthaphorn Trakarnsanga, Thawatchai Akaraviputh, Asada Methasate, Vitoon Chinswangwatanakul
Article DOI: 10.21614/sgo-25-5-248
Read article Background: Enhanced recovery after surgery (ERAS) protocol has been shown to reduce recovery period and postoperative complications. This prospective study aimed to evaluate the short-term outcomes of ERAS in patients who underwent upper gastrointestinal (UGI) surgery.

Methods: Patients who underwent surgery for benign or malignant diseases of the esophagus, esophagogastric junction, or stomach during October 2018-December 2019 were included. Outcomes compared between ERAS and conventional care (CC) included length of hospital stay (LOS), postoperative complica....[more]
Gastric and Extragastric GIST Presentation and Management, in a Tertiary Referral Center - A Ten Years Retrospective Cohort Study
Ahmed Abdallah, Mosab Shetiwy, Islam A Elzahaby, Basel Refky, Khaled AbdElwahab, Osama Eldamshety, Mahmoud Abdelaziz, Amr Abouzid, Nirmeen Megahed, Islam H Metwally
Article DOI: 10.21614/sgo-25-5-269
Read article Introduction: Gastrointestinal stromal tumor (GIST) is the commonest mesenchymal tumour of the gut. However, the epidemiology of the disease in Egypt is not adequately studied.

Methods: A retrospective cohort study was conducted on patients treated for GIST from June 2008 to April 2018 in a tertiary center. Sixty-two cases were eligible for the study.

Results: The stomach was the commonest tumor site. The incidence of tumor residue was higher in extra-gastric (intestinal) GISTs. Laparoscopy was more frequently used in gastric GIST surgery. Overall....[more]
Very Low Carbohydrate Diet Effect on Modified Glasgow Prognostic Score: A Randomized Controlled Trial on Stage-IV Colorectal Adenoca....
Vicky Sumarki Budipramana, Fransiscus Arifin
Article DOI: 10.21614/sgo-25-5-280
Read article Background: The stage-IV Colorectal adenocarcinoma patients who cannot be treated with any conventional cancer treatment (surgery, chemotherapy, or radiotherapy) belong to the best supportive care group. Very low carbohydrate diet reduces the glucose supply to the cancer cells through the specific metabolic pathway called the Warburg effect.
The cancer cell may "starve" and limit the growth that can be measured by the reduction of the systemic inflammation reaction using modified Glasgow Prognostic Score (mGPS). This study aimed to prove that a very low carbohydrate diet....[more]
Primary Splenic Melanoma Associated with Small Intestinal Serosal Implants Causing Intussusception - A Case Report
Omar Hamdy, Gehad A Saleh, Sara Raafat, Mohammad Zuhdy, Abdelhadi M Shebl
Images in Clinical Medicine, Dec 2020
Article DOI: 10.21614/sgo-25-5-286
Read article Introduction: Melanoma is a highly aggressive tumor that carries a poor prognosis. There are several reported cases of secondary splenic melanoma but there is only one reported case of primary splenic melanoma yet. Case presentation: A 35-year-old male, complaining from left lumbar pain.
Abdominal ultrasound revealed a mass at the lower pole of the spleen measuring 10x7x7 cm. Computed Tomography (CT) described a necrotic focal lesion involving its lower pole measuring 11 x 9 cm. US-guided fine needle aspiration (FNA) was suggestive of lymphoma, but tissue biopsy was reco....[more]
Laparoscopic Gastric Bypass in Patient with Giant Ventral Hernia
Pablo Valsangiacomo, Mauro Perdomo, Jimena Garmendia, Martin Bentancur, Daniel Gonzalez
Video Case Report, Dec 2020
Article DOI: 10.21614/sgo-25-5-292
Read article Introduction: Abdominal hernias are more frequent in obese patients, associating more complications and worse therapeutic outcomes. These patients require a multidisciplinary treatment approach, including bariatric and hernia teams, and carried out in a specialized center.

Objective: To present the case of a 42yo obese patient with giant ventral hernia, and to discuss our therapeutic approach. This is a video presentation of a case report and literature review about the state of the art for hernia repair in obese patients.

Case report: 42 year-....[more]

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Journal Abbreviation: Surg. Gastroenterol. Oncol.

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