Surgery, Gastroenterology and Oncology

Read article Background: Controversy has been reported concerning the extent of lymphadenectomy during esophageal adenocarcinoma (EAC) resection surgery in the era of multimodal therapy. Due to unfavorable biology, there is potential for the neoplasia to persist after neoadjuvant therapy. Extended lymphadenectomy might bring a survival advantage to these patients. This systematic review and meta-analysis evaluates whether the extension of lymphadenectomy has impact on overall survival (OS) in patients with EAC submitted to esophagectomy preceded by neoadjuvant therapy.

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Background: The efficacy of gelatin-thrombin matrix sealants (Floseal®) for hemostasis has been well described in the field of cardiovascular surgery, but data supporting its safety and efficacy in liver surgery remains lacking.

Methods: The surgical outcomes of 83 consecutive patients in whom Floseal® was applied during hepatectomy were reviewed. The severity of bleeding before and after the application of Floseal® was graded according to the Validated Intraoperative Bleeding (VIBe) Scale.

Results: Flo....[more]

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Background: HCV chronic infection is a leading cause of end-stage liver disease and liver transplantation. The aim of our study was to assess the benefits of novel anti-HCV therapeutic approaches in obtaining viral clearance, in reducing liver inflammation, in regression of fibrosis, and improvement of liver-related morbidity and mortality.

Material and methods: We performed an observational, prospective, non-interventional study in 260 patients with HCV chronic infection and advanced liver fibrosis (F3 and Child class A liver cirrhosis), ....[more]

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Background: The most common types of true epithelial exocrine pancreatic cystic neoplasms are serous cystic neoplasms (SCNs), mucinous cystic neoplasms (MCNs), intra-ductal papillary mucinous neoplasms (IPMNs), and solid pseudo-papillary neoplasms (SPPNs). Both open and laparoscopic pancreatic surgeries are major procedures with significant morbidity and mortality rates. This study aimed to determine the outcomes of laparoscopic pancreatic surgery in managing true exocrine epithelial pancreatic cystic neoplasms in terms of postoperative pancreatic fistula and recu....[more]

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Background: Gastrointestinal stromal tumours (GISTs) are uncommon sarcomas. Surgery and target therapy are the primary modalities in treating GIST. KIT expression is the cornerstone in diagnosis of GIST, yet its expression is absent in a small percent of GISTs. The precise behaviour and treatment effects, particularly target therapy, and the prognosis of these cases are unclear; hence this study was designed to investigate them.

 

Methods: In the current retrospective cohort research, all patients with GIST who presented and w....[more]

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Traumatic diaphragmatic hernia (TDH) is an uncommon disease, with an incidence of about 0.5% and is usually associated with penetrating or blunt thoracoabdominal trauma (1). It is often associated with other thoracoabdominal, brain and musculoskeletal injuries, being a diagnostic and therapeutic challenge (2). These injuries worsen the prognosis, with a mortality of up to 31% (2, 3). Chest X-rays with bowel contrast studies and CT scans of the chest and the abdomen are a useful diagnostic tool for detecting TDH, being the latter more specific (4). The treatment involves repair of ....[more]

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Budd-Chiari syndrome (BCS) represents a rare medical entity which has an estimated incidence of 0.1 to 10 people per million every year. It is defined by the obstruction of the flow in the inferior vena cava or the hepatic veins. Various classifications have been proposed. So, it can be acute or chronic and primary or secondary. The chronic form is more frequent and is characterized by signs of portal hypertension. Liver transplantation is the ultimate therapeutic management of Budd-Chiari syndrome. Primary BCS is mostly a result of hematological disorders and hypercoagulable cond....[more]

Read article Benign mesothelial mesenteric cysts constitute a rare clinical entity and usually are discovered incidentally during abdominal imaging essays. Very infrequently though, they can become acutely symptomatic due to occurrence spontaneous rupture, hemorrhage or compression of adjacent organs, due to their dimensional progression. Herein, we present a rare case of symptomatic, extrinsic colonic compression secondary to the presence of a large mesothelial mesenteric cyst, which was abutting the left colon, causing persistent alteration of colonic habits.

CASE DESCRIPTION

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