Surgery, Gastroenterology and Oncology

Purpose: To describe correlation of benign non-HPV associated perianal conditions and HIV status in patients seen at Princess Marina Hospital.

Methods: A one-year (January - December 2017) retrospective study conducted at Princess Marina Hospital, Gaborone. The University of Botswana, Ministry of Health and Princess Marina Hospital granted ethical clearance. Data was collected from the Accident and Emergency department triage forms and medical records.

Results: One hundred and fourteen (114) patient files were reviewed. Sixty-six (66) were male and 44 were female. The mean age was 35.0 years (SD = 11.9). Of the 114 patients 68 were HIV negative, 40 were positive and 6 had unknown HIV status. The commonest diagnosis was haemorrhoids accounting for 56.1% (64 114) followed by perianal abscess & fistulae in ano at 36.0% (41 114). In the HIV positive group, the infectious perianal conditions occurred in patients with a relatively lower mean CD4 count. Abscesses & fistulae in ano are more common in HIV positive patients while haemorrhoids and anal fissures are common in HIV negative patients. The above-mentioned association was found to be statistically significant (p<0.001).

Conclusion: The commonest non-HPV-associated perianal condition presenting at PMH is haemorrhoids followed by perianal abscess & fistula in ano. HIV positive patients tend to develop perianal abscesses & fistulae in ano. HIV positive patients who present with infectious pathologies tend to have a relatively lower CD4 count.

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