Surgery, Gastroenterology and Oncology

Abstract

Introduction: Pancreatic neuroendocrine tumors (PNETs) are uncommon, representing fewer than 5% of all pancreatic malignancies. They are a diverse group of tumors with different biological behaviors, clinical features, and prognostic outcomes. Reported 5-year survival varies widely, from 25% up to 100% in some series. Aim: Evaluate recurrence

patterns, risk factors, and their influence on disease free survival (DFS) and overall survival (OS).

Methods: Retrospective review of 87 patients undergoing cu....[more]

Abstract

Introduction: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the digestive system, with diverse histopathological and clinical features. This study aimed to analyze the clinical and pathological characteristics as well as surgical outcomes of GIST patients treated at our institution.

Methods: We retrospectively reviewed 49 patients who underwent surgery for GIST at Dicle University between 2010 and 2020. The collected data included demographic information together with tum....[more]

ABSTRACT

Background: This retrospective comparative study evaluated the impact of wound edge protector use on surgical site infection (SSI) rates in patients undergoing open appendectomy for acute appendicitis.

Methods: Medical records from Vajira Hospital (2020–2023) were reviewed. Propensity score matching was used to adjust for baseline characteristics. All patients received peri-operative intravenous antibiotics and 4% chlorhexidine antiseptic skin preparation. Outcomes including SSI, blood loss, pain scores, ....[more]

Abstract

Introduction: Hemorrhoids are the most common benign anorectal condition, significantly impairing patients’ quality of life. When medical treatment fails, surgery becomes necessary. In recent years, minimally invasive techniques have gained attention and been increasingly applied in clinical practice. Objective: This study aimed to evaluate the outcomes of TND’s Vertical Ligation-Mucopexy (TVLM) in the treatment of circumferential hemorrhoids at Hanoi Medical University Hospital.

Methods: A retrospectiv....[more]

ABSTRACT

Background: One of the most crucial elements in assessing breast cancer prognosis is axillary lymph node status. While ultrasonography (US) is routinely used for pre-therapeutic axillary evaluation, its diagnostic performance post-neoadjuvant chemotherapy (NAC) requires further validation. Objective: To evaluate the reliability and accuracy of ultrasound assessment of axillary lymph nodes before and after neoadjuvant chemotherapy, comparing it with sentinel lymph node biopsy and final paraffin histopathological findings in post-neo....[more]

ABSTRACT

Background and Aim: The Thyroid Imaging Reporting and Data System (TIRADS) and Bethesda cytopathology classification are widely used to stratify malignancy risk in thyroid nodules; however, their diagnostic fallacies remain understudied in multicenter cohorts. This study evaluated the accuracy and limitations of the TIRADS and Bethesda systems in differentiating benign from malignant thyroid nodules across multiple centers.

Materials and Methods: A multicenter cohort of 500 patients with thyroid nodules ....[more]

Introduction

Cervical cancer ranks as the second leading malignancy among women, particularly in developing regions where organized screening and HPV vaccination programs remain limited. Despite advances in prevention, the disease continues to represent a serious public health challenge. Globally, the incidence rate is estimated at 13.3 per 100,000 women-years, with a mortality rate of approximately 7.2 per 100,000 women-years (1).

Persistent infection with high-risk HPV types is the main causal factor in cervical carcinogenesis. Following epithelial....[more]

Abstract

Background: Dieulafoy’s lesion, an uncommon cause of upper nonvariceal bleeding, is a submucosal vessel that erodes the near normal appearing mucosa without primary ulceration or erosion. The lesion occurs predominantly in the stomach, but it is also reported in extragastric sites.

Case and review of the literature: We present the case of a 69 years old patient, who presented in the emergency department with massive upper gastrointestinal bleeding caused by a duodenal Dieulafoy’s lesion. Risk factors i....[more]

ABSTRACT

Background: Congenital intestinal malrotation is a rare developmental anomaly due to incomplete rotation and fixation of the midgut during fetal life. Though predominantly identified in infancy, it can exceptionally present in adulthood, often with nonspecific symptoms that pose a significant diagnostic challenge. This case report discusses an adult presentation of intestinal malrotation complicated by volvulus, with successful surgical management. A comprehensive review of the literature is also provided, highlighting the embryolo....[more]

ABSTRACT

Postoperative recurrence of cancer in patients with p-stage I rectal cancer is rare. Lung or liver metastases from colorectal cancer have been commonly reported. We observed an extremely rare metastasis, namely, vaginal metastasis, from p-stage I rectal cancer one year after surgery. An 82-year-old female patient underwent laparoscopic high anterior resection for p-stage I upper rectal cancer. She received no adjuvant chemotherapy after surgery. Preoperative positron emission tomography combined with computed tomography (PET/CT) revealed no distant....[more]