2023 - September
Introduction: Laparoscopy can diagnose and treat the etiologies of acute upper abdominal pain. This study aimed to assess the effectiveness of laparoscopy in upper gastrointestinal (G.I.T) emergencies regarding intraoperative and postoperative outcomes.
Method: A retrospective observational study was conducted in the emergency departments of Zagazig University on 215 patients who had upper abdominal emergency surgeries between June 2017 and June 2020.
Results: The majority of patients (68%) were £ 40 years ol....[more]
Introduction: Lower abdominal pain is caused by various gastrointestinal tract (GIT) emergencies, including acute appendicitis, intestinal obstruction, acute perforated diverticulitis, obstructed hernia, and iatrogenic colon perforation. Therefore, laparoscopy may be of diagnostic and therapeutic value.
Methods: Between April 2017 and April 2020, 793 patients with lower GIT emergencies, including acute appendicitis, acute intestinal obstruction, complicated colonic diverticulum, complicated hernias, and iatrogenic colonic perforations, wer....[more]
Malignant obstructive jaundice (MOJ) is a disease that could negatively affect patient outcomes. It is treated with Endoscopic Retrograde Cholangiopancreatography (ERCP), Percutaneous Transhepatic Biliary drainage (PTBD), or Endoscopic ultrasound-guided biliary drainage (EUS-BD). We here present a case where malignant obstructive jaundice that failed both ERCP and PTBD achieved successful biliary decompression through trans-cholecysto-cystic duct CBD stenting. A-53-year old female presented to our center with obstructive jaundice secondary to a pancreatic uncinate tumor. Multiple ....[more]
2023 - March
Background: Hepatitis C is a worldwide problem. The hepatitis C virus (HCV) is a major cause of both acute and chronic hepatitis. The World Health Organization (WHO) estimates about 71 million people globally have chronic hepatitis C accounting for 1% of the population.
Objectives: This study aims to investigate the response of liver fibrosis to direct-acting antiviral drugs (DAADs) used in the treatment of chronic hepatitis C infection in different stages of fibrosis regarding several non-invasive biochemical markers.
Introduction: Volvulus of the ascending colon is a rare cause of large bowel obstruction and presents because of its mesentery with excessive mobility allowing it to rotate on its axis. It is usually due to a congenital or acquired anatomical variation.
Objective: To describe volvulus of the ascending colon as a rare complication in a young patient, whose diagnosis was mistaken for sigmoid volvulus and diaphragmatic hernia.
Case report: We present the case of a 27-year-old woman who pr....[more]
Background: The probability of lateral compartment recurrence is significantly increased in rectal cancer diagnosed patients with clinical evidence of Lateral Pelvic Lymph Node (LPLN) metastases if they get Total Mesorectum Excision (TME) without LPLN dissection, even if they undergo combined-modality chemoradiation therapy (nCRT).
Objectives: The objective of this study is to determine the minimum post neoadjuvant chemoradiotherapy LPLN size that reliably predicts lymph node positivity.
Patien....[more]
Objective: Evaluation of our management of acute or chronic traumatic diaphragmatic hernia repair with sutures or mesh.
Patients and methods: Between January 2014 and January 2019, a retrospective study on 185 patients with acute and chronic traumatic diaphragmatic hernias was carried out at the general surgery department of Zagazig University. Results both during and after surgery were assessed.
Results: The median age of the patients was 42.6±8.3 years, with 81% being male. Bl....[more]
2023 - January
Background: High-risk cases for NAFLD are currently underreported or not identified in a timely manner. It is important to elucidate the clinical behavior of the interaction of clinical values in metabolic syndrome (MetS) and non-alcoholic fatty liver disease (NAFLD), considering the complications that may occur in the group of patients with this comorbidity.
Methods: A total of 1,604 adults diagnosed with metabolic syndrome (MetS) and non-alcoholic fatty liver disease (NAFLD) were randomly selected for a cross-sectional study. Metabolic s....[more]
We present the case of a 62 year old male with no relevant medical history, who for the last two months had been complaining of dysphagia for solids and liquids, marked physical fatigue, oliguria. Clinical examination revealed palor and dehydrated skin, as well as a tumoral mass of 10/10 cm palpable in the upper abdomen. Upper digestive endoscopy was performed, showing a vegetant lesion of 6 cm on the gastric angle, with a central ulcer of 4 cm. The oesophagus and duodenum were normal, and Helicobacter pylori test was negative. Histological exam from the gastric les....[more]
2022 - October
Abstract
Background: The parameters used for predicting choledocholithiasis include clinical presentations, liver function tests, and imaging. Moreover, prediction is essential so as to select suitable therapeutic modalities, which are typically not available in primary hospitals. Thus, a time gap commonly occurs. In this study, we aimed to assess the incremental yield of choledocholithiasis prediction if liver function tests or ultrasonography were repeatedly performed.
Methods: This was a retrospectiv....[more]
Abstract
Background: In spite of a more efficient approach to upper digestive bleedings over the past three decades, acute oesophageal variceal bleeding remains a severe and deadly complication in the cirrhotic patient life, which marks a turning point in the evolution of their liver disease.
Aim and Objectives: To determine the frequency of duodenal ulcer (DU), as well as other clinical characteristics occurring after endoscopic variceal ligation (EVL) of the esophagus, Subjects and methods; The curren....[more]
Abstract
Objectives: Recently, there are emerging evidence of sepsis related ruptured appendicitis caused by multi-drug resistant gram-negative bacteria including carbapenems. Our study’s aim was to explore the clinical and non-clinical differences between Colistin+Tigecycline (Group I) and Colistin+Meropenem (Group II) in septic critically ill patients after perforated appendicitis during emergent surgical appendectomy.
Methods: A single-center observational retrospective study was processed in c....[more]
ABSTRACT
Hepatic Mesenchymal Hamartoma (HMH) is a congenital benign tumor, with an uncertain pathogenesis. Most of them are diagnosed during childhood and they are exceptional in adults. We present a case of a young adult with a hepatic tumor in the segments IV-V, initially described as an adenoma and then, five years later definitely diagnosed with HMH. The tumor was completely resected with free margins because of its volume increase and risk of malignization. We study the clinical presentation until the final pathology. The analysis of its possibl....[more]
2022 - July
Objectives: The aim of this study is to determine overall survival rate, tumor recurrence rate, and associated factors for recurrence. Materials and
Methods: A retrospective chart review of patients admitted to Siriraj Hospital with SCT (2000-2018) was performed. Data were collected and analyzed for the association with outcomes, including survival rate, and tumor recurrence....[more]
Methods: This randomized, preâ?"post-control design study was conducted on adult patients undergoing routine hemodialysis. Patients were divided equally into two groups. In addition to the standard protocol, the first group was g....[more]
2022 - March
ABSTRACT
Background: Rapid developments in molecular biology in recent years have made possible the discovery of several new prognostic factors in addition to the previously known ones. Changes in proto-oncogenes and suppressor genes play an important role in the pathogenesis of cancer.
The proto-oncogene Ki-67 and the suppressor gene P53 are prognostic and predictive markers for the level of proliferation.
This study aims to determine the association between Ki-67 and P53 in patients wit....[more]
ABSTRACT
Introduction: Breast cancer is a heterogeneous disease that encompasses a wide range of pathological entities and clinical behaviors. It is classified into several subtypes based on their histopathological characteristics, tumor grade and biological features. This classification is important for studying breast cancer etiology, predicting clinical course, and making decisions related to breast cancer treatment. This study aims to identify biological characteristics of breast cancer among a group of Jordanian women who were refer....[more]
ABSTRACT
We report a rare case of invasive papillary carcinoma of the breast in a 41-year-old man. The patient presented with a newly diagnosed symptomatic mass in his left breast of incidental finding. He had no concomitant disease at the time of diagnosis and had never received radiation therapy; he denied a family history of first- or second-degree cancer. Clinical examination showed a fixed mass. Biopsy revealed a solid low-grade intraductal papillary carcinoma with necrosis and a suspected microinvasive focus with high estrogen and progestero....[more]
ABSTRACT
Primary renal non-Hodgkin lymphoma is a rare extra-nodal lymphoma with a progressive characteristic and poor prognosis. We report on the case of a 73-year-old female with a painful right upper quadrant mass. The patient was planned for radical nephrectomy via laparotomy based on suspicion of renal cell carcinoma, shown on a urography CT scan. Intraoperatively, we identified a huge, solid, fixed mass originating from the right kidney; thus, a biopsy was performed. Histopathology and immunohistochemistry results showed a diffuse large B-cel....[more]
2021 - December
5% of bowel obstruction comes with intussusception, while adult intussusception only represents 1% of all bowel obstruction, and of all hospital requirement only 0.003%-0.02%. We report an unusual case of MPM metastasized to the lungs and brain in a 56-year-old male who presented with chronic nonspecific abdominal symptoms. Computed tomography (CT) scans revealed apical pleural mass with ileocaecal intussuception. ....[more]
Methods: A prospective study on 42 patients who underwent laparoscopic distal gastrectomy with Billroth II â?" Braun an....[more]
2021 - November
Background: Esophageal varices (EV) are dilated submucosal distal esophageal veins connecting the portal and systemic circulations. This happens due to portal hypertension (most commonly a result of cirrhosis), resistance to portal blood flow, and increased portal venous blood inflow. The most common fatal complication of cirrhosis is variceal rupture.
Patients and methods:....[more]
Methods: This study was conducted on 84 cases with residual gallbladder remnant stone or cystic duct st....[more]
2021 - September
Methods: This study includes 70 patients with various grades of splenic injuries in abdominal trauma. The patients were 15 years and older. They were categorized into two groups: open splenectomy gro....[more]
Methods: A one-year (January - December 2017) retrospective study conducted at Princess Marina Hospital, Gaborone. The University of Botswana, Ministry of Health and Princess Marina Hospital granted ethical clearance. Data was collected from the Accident and Emergency department triage forms and medical records.
Results: One hundred and fourteen (114) patient files were reviewed. Sixty-six (66) were male ....[more]
Surgical resection remains the first option for the treatment and should be performed in Centers with adequate experience. We report a case of metastatic liver tumor from an atypical meningioma and reviewed similar previously publishedcases, summarizing potential risk fa....[more]
2021 - July
Methods: The study sample was patients with benign prostatic hyperplasia (BPH) and cancer of the prostate (CaP) in Makassar, Indonesia. Statistical tests were performed with the Mann-....[more]
Methods: This was a prospective study where patients presenting with breast lump with a trucut FNAC report suggestive of benign or maligna....[more]
Methods: This is a retrospective cohort study. Ki-67 data was fro....[more]
Methods: A retrospective study of 1510 patients who underwent appendectomy for a presumptive diagnosis of appendicitis from January 2011 to December 2017. The aim of this study is to review appendectomy specimens regarding diagnostic accuracy....[more]
Methods: Locally advanced esophageal cancer patients who received neoadjuvant or definitive CRT at our institution were retrospectively reviewed. After completing CRT, combined endoscopy and CT findings were used to define cCR, and t....[more]
Methods: A retrospective study was conducted from January 2016 to December 2019.
Results: We found nine patients, mainly were male (n=5), in the sixth decade of life. Most of these injuries were secondary to gallbladder and bile duct procedures (n=5). The average time elapsed between injury and repa....[more]