Surgery, Gastroenterology and Oncology
Vol. 25, No. 1, Feb 2020
Locally Advanced Gastric Cancer: Current and Future Strategies to Improve Outcomes with Multimodality Approach
Elisabete Couto, Ana Marques, Diana Freitas, Rui Nabiço
REVIEW, Feb 2020
Article DOI: 10.21614/sgo-25-1-17
Gastric cancer is the sixth most common cancer and the fourth most common cause of cancer- related death in Europe, causing 107.000 deaths every year. Locally advanced gastric cancer (LAGC) can be defined as clinical T2 disease and beyond with or without confirmed nodal involvement.
Surgery is the cornerstone of therapeutic strategies with curative intent, but a significant amount of patients relapse after surgery and 5-year survival rates remain poor (1).
Active research on multimodality approach, adding chemotherapy and or radiotherapy to optimal surgery allowed improvement of survival in the past two decades.

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Journal Abbreviation: Surg. Gastroenterol. Oncol.

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