Nowadays gastric cancer is still considered a fatal disease, in spite of the declined incidence and mortality due to the advances in treatment, postoperative care, and multimodality therapy.
It was made a systematic research of literature published regarding gastric cancer and lymphadenectomy in locally advanced ones. Surgical resection with appropriate lymphadenectomy is still the best chance for long-term survival for patients with gastric cancer. Lymph node status is a major determinant of disease recurrence after patients undergo curative surgery.
When performed in centers with experience, in a least invasive way, D2 lymphadenectomy is the procedure of choice in the treatment of locally advanced gastric cancer, guaranteeing the best survival rate.
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