Surgery, Gastroenterology and Oncology
Vol. 21, No. 2, June 2016
The Association Between Inflammation and Angiogenesis in Human Pancreatic Adenocarcinoma
Cristiana Tanase, Laura Georgiana Necula, Ana Iulia Neagu, Radu Albulescu
REVIEW, June 2016
Article DOI: 10.21614/jtmr-21-2-78
Pancreatic cancer represents one of the deadliest cancers with a high mortality rate, characterized by an aggressive local invasion and early metastases. This malignancy is poorly responsive to chemotherapy or chemo-radiotherapy. Several proangiogenic factors were associated with pancreatic carcinogenesis, highlighting the importance of using antiangiogenic agents as therapeutic strategy.
Further studies suggest the involvement of chronic inflammation in angiogenesis processes in pancreatic carcinogenesis and inflammatory cytokines should be considered as potential biomarkers, as well as therapeutic targets in pancreatic cancer patients.

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Cited by 1 articles

Journal: Journal of Immunology Research (2314-7156)
Article: A Morphological and Immunohistochemical Study of the Tumoral and Inflammatory Cells in Pancreatic Ductal Adenocarcinoma
Crossref DOI: 10.1155/2020/6148286

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ISSN: 2559 - 723X (print)

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ISSN-L: 2559 - 723X

Journal Abbreviation: Surg. Gastroenterol. Oncol.

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