Surgery, Gastroenterology and Oncology

Introduction: Ductal carcinoma in situ (DCIS) is rarely diagnosed in young female patients with most studies view age as a poor prognostic factor.

Patient and Methods: Female patients who underwent surgery for DCIS of the breast (with or without microinvasion) in our department between February 2007 and February 2022 were included. They were divided into two groups: group I (<40 years old) and group II (³40 years old), aiming to evaluate and compare the clinical-epidemiological, pathological, radiological, operative, and outcome data be....[more]

Background: Hereditary factors play a major role in breast cancer development, making it a serious global health concern for women. This study aimed to determine if RAD51 gene polymorphism rs1801320 (135 G>C) increases breast cancer risk in women in Thi-Qar Province, Iraq.

Methods: Forty women with breast cancer and twenty healthy volunteers participated. Data from blood samples were analyzed using Chi-square tests and odds ratios for PCR-based genotyping.

Results: The RAD51 gene variant rs1801320 did not show a....[more]

Background: Treatment of metastatic colorectal cancer (mCRC) with BRAFV600E mutation is challenging. Resistance to treatment is a significant cause of unfavourable clinical outcomes. Aim: This work investigated the effectiveness and safety of bevacizumab (BEV) mFOLFOXIRI as an initial line of treatment of mCRC with BRAF V600E mutation.

Materials & Methods: This prospective, phase II, open-label study included 30 participants with mCRC harboring RAS wild-type and BRAF V600E mutation in primary tumors or metastases. Patients received 5 mg....[more]

Background: Polypropylene meshes are widely used in hernia repair, with design and placement techniques significantly impacting postoperative outcomes. Merigrow™ Mesh is a microporous, lightweight polypropylene mesh that improves tissue integration while minimizing complications such as seroma, chronic pain and surgical site infections (SSI). This study evaluated its safety profile under real-world surgical conditions. Aim: To evaluate Merigrow™ Mesh safety and performance in elective hernia repair patients in a retrospective observational study.

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Introduction: Globally, gliomas account for > 70% of all brain tumors. In Iraq, there is a tendency towards a higher rate of gliomas. The Iraqi Cancer Registry in 2019 stated that central nervous system tumors were among the top three cancers in Iraq and the top ten cancers in Sulaymaniyah.

Method: In this hospital-based frequency analysis study, information from 104 glioma patients was reviewed. Data were then subjected to critical analysis, taking into consideration all relevant factors related to demographic data (age, sex, and ethni....[more]

Background: Hepatocellular carcinoma (HCC) is the sixth most common cancer worldwide and the third most common cause of cancer mortality. Underlying liver cirrhosis is the strongest predisposing factor for HCC. Many patients with HCC are diagnosed at an advanced stage when curative treatment is no longer feasible. Early detection of HCC is crucial for providing effective initial treatments. Fibroscan, a non-invasive, reproducible tool for assessing liver stiffness, may help identify patients with liver cirrhosis at high risk of developing HCC. Objective: To evalua....[more]

Inguinal hernia is a common surgical condition worldwide and involves protrusion of an organ or its fascia through the abdominal wall. The hernia contents may include omentum, colon, small bowel, or its mesentery, while less common contents such as the appendix, ovary, or fallopian tube can also be present. Amyand’s hernia, in which the appendix is found within the sac, is one such rare form. We present a case of a 48-year-old male with a long-standing history of reducible right inguinal hernia who presented with acute onset right inguinal scrotal pain requiring emergency open r....[more]

A young gentleman presented with one day history of severe right sided abdominal pain with no other relevant history and normal blood work. Diagnostic laparoscopy revealed an omental infarct and resection was performed. He was well post operatively and discharged the following day.

BACKGROUND

Omental infarct is a rare cause of abdominal pain and usually has a similar presentation to appendicitis, cholecystitis, or diverticulitis. The first diagnosis of omental infarction was made by Bush in 1986 and since then, approximately 400 cases....[more]